Eukaryotic cells contain an intricate and dynamic network of membrane bound organelles. The cytoskeleton shapes cells and the membrane trafficking machinery ensures that proteins and lipids are transported to the right place at the right time. BMCB laboratories investigate the function and regulation of the internal organization of eukaryotic cells. They use a wide range of approaches, including biochemistry, genetics, structural biology, and quantitative microscopy to advance the frontiers of this foundational area of cell biology.