The fundamental unit of life is the cell, and without enzymes life would not be possible. Core cellular behavior is controlled through interconnected metabolic pathways. Regulation of these pathways is critical for cell homeostasis, and dysregulation of metabolism is associated with disease. For example, diabetes is essentially a metabolic disease and the unique metabolism of cancer cells represents a promising therapeutic target. BMCB laboratories investigate the function and regulation of enzymes and metabolism using biochemical, structural, cell biological, and engineering approaches.
Research Area Faculty
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Mikail Abbasov, Assistant Professor Chemistry & Chemical Biology Research Interests: Professor Abbasov's highly interdisciplinary program at Cornell will advance innovative chemoproteomic technologies to modulate the function of proteins and interrogate signaling pathways associated with cancer and neurodegenerative disorders |
607-255-8864 mea254@cornell.edu Lab Website Publications |
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Joeva Barrow, Assistant Professor Human Ecology: Nutritional Sciences Research Interests: The Barrow lab studies mitochondrial biology and metabolism in the context of mitochondrial and metabolic disease. We leverage unbiased CRISPR and small molecule screening approaches to identify novel targets for therapy. |
607-255-9429 jb2254@cornell.edu Publications |
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Pamela Chang, Professor Microbiology & Immunology Research Interests: Host-microbe interactions, gut microbiome, microbiology, and immunology |
607-253-4079 pvc29@cornell.edu Lab Website Publications |
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Matthew DeLisa, William L. Lewis Professor of Engineering Chemical & Biomolecular Engineering Research Interests: applied immunology; glycobiology and glycoengineering; protein biogenesis; protein engineering; synthetic biology |
607-254-8560 md255@cornell.edu Lab Website |
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Martha Field, Assistant Professor Human Ecology: Nutritional Sciences Research Interests: My laboratory studies gene-nutrient-environment interactions, and underlying molecular mechanisms, that lead to development of pathology. We currently focus on folate and vitamin B12 metabolism as well as central/glucose metabolism. |
607-255-6081 mas246@cornell.edu Lab Website Publications |
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Martin Graef, Assistant Professor Molecular Biology & Genetics Research Interests: understanding the molecular mechanisms & physiological functions of autophagy, a conserved intracellular degradative process using a multidisciplinary approach including genetics, cell biology, and biochemistry in budding yeast and mammalian cell culture |
607-255-2203 mg2255@cornell.edu Publications |
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Laura Gunn, Assistant Professor Integrative Plant Sciences Research Interests: We study the sequence-structure-function of nature’s carbon-fixing enzyme, Rubisco, using structural biology, synthetic biology and protein engineering approaches. |
607-279-9952 lhg42@cornell.edu Publications |
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Maureen Hanson, Liberty Hyde Bailey Professor Molecular Biology & Genetics Research Interests: In order to identify the molecular basis and biomarkers of the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, the Hanson lab examines proteins, metabolites, vesicles cargoes in blood, immune cells, and tissues. |
607-254-4833 mrh5@cornell.edu Lab Website Publications |
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Hening Lin, Professor Chemistry & Chemical Biology Research Interests: Enzyme function and regulation of metabolism |
607-255-4650 hl379@cornell.edu |
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Maurine Linder, Professor Molecular Medicine Research Interests: Regulation of signal transduction and protein trafficking by protein lipidation |
607-253-3893 mel237@cornell.edu Publications |
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Zeribe Nwosu, Assistant Professor Molecular Biology & Genetics Research Interests: Research in the Nwosu Lab focuses on understanding the metabolic alterations that drive cancer, the involvement of tumor microenvironment cells in modulating metabolism, and ways to effectively target metabolism to improve cancer treatment. |
zcn3@cornell.edu Lab Website Publications |
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Frank Schroeder, Professor Boyce Thompson Institute Research Interests: The Schroeder lab investigates small molecule signaling in C. elegans, mouse, and humans, with a focus on host-microbe interactions, using high-resolution mass spectrometry- and NMR-based metabolomics as well as synthesis of new metabolites and chemical b |
607-254-4391 fs31@cornell.edu Lab Website |
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Aleksandra Skirycz, Assistant Professor Boyce Thompson Institute Research Interests: Functional characterization of small-molecules via cell wide characterization of protein-metabolite interactions; small-molecule regulation of central metabolism in model organisms; biochemistry, proteomics and metabolomics |
607-279-3720 as4258@cornell.edu Publications |
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Klaas van Wijk, Professor & Chair Integrative Plant Sciences Research Interests: Chloroplast proteostasis in plants with emphasis on proteases and discovery of degrons, using a combination of protein biochemistry, mass spectrometry, systems biology and molecular biology |
607-255-3664 kv35@cornell.edu Lab Website Publications |
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Meng Wang, Assistant Professor Division of Nutritional Sciences Research Interests: We aim to dissect how metabolism can cause DNA damage that impacts cancer development and aging, and to design novel treatments that target DNA damage pathways. We use genetic and mass spectrometry approaches in cell lines and animal models. |
607-254-2321 mengwang@cornell.edu Lab Website Publications |
