Sergiy Libert
Assistant Professor
Sergiy LIbert

Phone

607-253-3082

Address

Department of Biomedical Sciences
Cornell University
T3-006 Vet Research Tower
Ithaca, NY 14853

Email

Web Sites

Department Profile

Lab Website

Background

Sergiy Libert is an Assistant Professor in the Department of Biomedical Sciences. He received a B.S. degree in Physics from Kiev-Mohyla Academy, Kiev, Ukraine in 2001, a M.S. degree in Physics from Clarkson University, Potsdam, NY in 2003, and a Ph.D. degree in Cell and Molecular Biology from Baylor College of Medicine, Houston, TX in 2007. He did his postdoctoral research at the Massachusetts Institute of Technology, Cambridge, MA from 2007-2013. In 2014, he was appointed as an Assistant Professor in the College of Veterinary Science at Cornell University.

Research Description

Most living organisms, including humans, age. Over time the ability to do physical and intellectual work deteriorates, and susceptibility to infectious, metabolic, and neurodegenerative diseases increases, which leads to general fitness decline and ultimately to death. Work in model organisms has demonstrated that genetic and environmental manipulations can prevent numerous age-associated diseases, improve health at advanced age, and increase life span.

My laboratory uses a diverse range of techniques to study the process of aging. We use mouse models, cell culture, biochemistry, and computational methods to better understand normal and pathological processes that accompany human aging, and to develop interventions to delay aging and ameliorate age-related diseases such as cancer, metabolic syndrome, and neuro-degeneration.

Selected
Publications

Sergiy Libert, Leonard Guarente, Metabolic and neuropsychiatric effects of calorie restriction and sirtuins, Annu Rev Physiol., 2013, 75:669-84.

Sergiy Libert, Kelli Pointer, Michael Bonkowski, Scott D. Pletcher, Leonard Guarente, Deviation of innate circadian period from 24 hours reduces longevity in mice, Aging Cell, 2012, Oct; 11:794-800.

Sergiy Libert, Kelli Pointer, Eric L. Bell, Abhirup Das, Dena Cohen, John M. Asara, Karen Kapur, Sven Bergmann, Martin Preisig, Takeshi Otowa, Kenneth S. Kendler, Xiangning Chen, John M. Hettema, Edwin J. van den Oord, Justin P. Rubio, Leonard Guarente, SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive, Cell, 2011, Dec 23; 147:1-14.

Sergiy Libert, Dena Cohen, Leonard Guarente, Neurogenesis directed by SIRT1, Nat. Cell Biol., 2008, Apr; 10(4):373-4.

Sergiy Libert, Scott D. Pletcher, Influence of environment perception on longevity and rate of aging, Cell, 2007, Dec 28; 131(7):1231-4.

Sergiy Libert, Yufang Chao, Jessica Zwiener, Scott D. Pletcher, Realized immune response is enhanced in longlived puc and chico mutants but is unaffected by dietary restriction, Molecular Immunology, 2008, Feb; 45(3):810-7.

Sergiy Libert, Insights into Physiology of Aging and novel ways to increase lifespan, Fly, 2007, 1(2):113-5.

Sergiy Libert, Jessica Zwiener, Xiaoween Chu, Wayne VanVoorhies, Gregg Roman, Scott D. Pletcher, Regulation of Drosophila lifespan by olfaction and food-derived odors, Science, 2007, Feb (315):1133-7.

Sergiy Libert, Yufang Chao, Xiaoween Chu, Scott D. Pletcher, Trade-offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFkB signaling, Aging Cell, 2006, Dec. 5(6):533-43.

Scott D. Pletcher, Sergiy Libert, Daniella Skorupa, Flies and their Golden Apples: The effect of diet on Drosophila aging and age-dependent gene expression, Aging Research Reviews, 2005, 4:451-80.

Sergiy Libert, Dan Goia, Egon Matijevic, Internally Composite Uniform Colloidal Cadmium Sulfide Spheres, Langmuir, 2003, 19:10673-178.

Sergiy Libert, Vyacheslav Gorshkov, Vladimir Privman, Dan Goia, Egon Matijevic, Model of Controlled Synthesis of Uniform Colloid Particles: Cadmium Sulfide, Langmuir, 2003, 19:10679-83.

Sergiy Libert, Vyacheslav Gorshkov, Vladimir Privman, Dan Goia, Egon Matijevic, Formation of Monodispersed Cadmium Sulfide Particles by Aggregation of Nanosize Precursors, Adv. Colloid Interface Sci. 100-102, 2003, 169-83.

Yaroslav Gotsulyak, Tamara Berdyyeva, Sergiy Libert, Effects of T-type calcium channel blockers on spontaneous meiotic maturation of mouse ovarian oocytes in vitro, Physiologíchny Jurnal, 2002, 48(1):98-101.

Tamara Berdyyeva, Sergiy Libert, Yaroslav Gotsulyak, The role of nitrogen monoxide in antibody influence on spontaneous electrical and contractile activity of rat’s smooth muscles, Physiologíchny Jurnal, 2000, 46(2):53.

Sergiy Libert, Tamara Berdyyeva, Yaroslav Gotsulyak, From mechanisms of immune infertility to new contraceptive means, Physiologíchny Jurnal, 2000, 46(2):74.