Daniel Barbash
Assistant Professor

Phone

607-254-5208

Address

Department of Molecular Biology & Genetics
401 Biotechnology Building
Cornell University
Ithaca, NY 14853-2703

Email

Web Sites

Background

Daniel Barbash is an Assistant Professor in the Department of Molecular Biology and Genetics. He received a B.S. degree in Biology from the Massachusetts Institute of Technology in 1989 and a Ph.D. in Genetics from the University of California, Berkeley in 1995. He did postdoctoral research in the Department of Genetics at the University of Cambridge with support from a NSF / Sloan Foundation Fellowship in Molecular Evolution, and in the Section of Evolution and Ecology at the University of California, Davis with support from the NSF. He joined the Cornell faculty in 2004.

Research Description

Regulation and molecular evolution of proteins involved in chromatin binding, RNA interference and stem-cell maintenance

Publications

N. J. Brideau*, H. A. Flores*, J. Wang*, S. Maheshwari, X. Wang and D. A. Barbash. Two Dobzhansky-Muller genes interact to cause hybrid lethality in Drosophila.  Science, 314: 1292 - 1295 (2006).  (*These authors contributed equally).

D.A. Barbash and J.G. Lorigan. Lethality in Drosophila melanogaster / Drosophila simulans species hybrids is not associated with substantial transcriptional misregulation. JEZ Part B: Molecular and Developmental Evolution. Published online Oct. 30, 2006.

D.A. Barbash*, P. Awadalla*, and A.M. Tarone. Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus.  PLoS Biology, 2: 839-848 (2004). (*These authors contributed equally).

D.A. Barbash, J. Roote, G. Johnson and M. Ashburner. A new hybrid rescue allele in Drosophila melanogaster. Genetica, 120: 261-266 (2004).

D.A. Barbash, D.F. Siino, A.M. Tarone, and J. Roote. A rapidly evolving MYB-related protein causes species isolation in Drosophila. Proc. Natl. Acad. Sci. USA 100: 5302-5307 (2003).

D.A. Barbash and M. Ashburner. A novel system of fertility rescue in Drosophila hybrids reveals a link between hybrid lethality and female sterility. Genetics 163: 217-226 (2003).

D.A. Barbash, J. Roote, and M. Ashburner. The Drosophila melanogaster Hybrid male rescue gene causes lethality in both male and female species hybrids. Genetics 154: 1747-1771 (2000).